Nelson, Karen E.


Cultivation of a human-associated TM7 phylotype reveals a reduced genome and epibiotic parasitic lifestyle

He et al. (2015). Proceedings of the National Academy of Sciences 112 (1)
Ca. Nanosynbacter
Significance TM7 is one of the most enigmatic bacterial phyla among the uncultivated candidate phyla referred to as “microbial dark matter,” and it has potential pathogenic associations. We revealed molecular insights into its uncultivability and pathogenicity, as well its unique epibiotic and parasitic lifestyle phases. These novel discoveries shed significant light on the biological, ecological, and medical importance of TM7, as well as providing useful information for culturing othe