Megasphaera intestinihominis

Marked as incorrect name

Citation

Formal styling
Megasphaera intestinihominis Hitch et al. 2025
Effective publication
Hitch et al., 2025
SeqCode status
Valid (ICNP)
Canonical URL
https://seqco.de/i:48062

Nomenclature

Rank
Species
Syllabication
in.tes.ti.ni.ho.mi'nis
Etymology
L. neut. n. intestinum, the intestine; L. masc. n. homo, a human being; N.L. gen. n. intestinihominis, of the human gut
Nomenclatural type
Strain sc|0041175: CLA AA-H81 = DSM 118069 = LMG 33597 (Cat. ) Lookup StrainInfo
Nomenclatural status
Validly published under the ICNP

Taxonomy

Description
The genome size is 2.38 Mbp, G+C percentage is 53.59%, with 100.00% completeness and 0.0% contamination. The closest relative to strain CLA-AA-H81 was Megasphaera indica (99.09%) based on 16S rRNA gene analysis. ANI comparison to all close relatives were below species assignment threshold (highest to Megasphaera elsdenii, 90.78%). GTDB-Tk classification as ‘Megasphaera sp000417505’ supports the creation of a novel species. Functional analysis showed the strain has 133 transporters, 16 secretion genes, and predicted utilization of starch, and production of butyrate, propionate, L-glutamate, folate, riboflavin, and cobalamin. Ecological analysis identified 152 matching (MASH distance < 0.05) MAGs, of which 124 originate from the human gut, suggesting this species is most commonly observed within this environment. This is supported by ecological analysis using 16S rRNA gene amplicon datasets which identified it within 19.0% of 1,000 human gut samples, with a relative abundance of 2.14 ± 5.23%. The strain CLA-AA-H81 (phylum Bacillota, family Veillonellaceae) was isolated from human faeces.
Classification
Bacteria » Bacillota » Negativicutes » Veillonellales » Veillonellaceae » Megasphaera » Megasphaera intestinihominis
Parent
Megasphaera ncbigtdb
Taxonomic status
Synonym, not recommended for medical use
Correct name
Megasphaera indica

Metadata

Outside links and data sources
Search sequences
Local history
Registered
Over 1 year ago by Masson, Johannes
Submitted
9 months ago by Masson, Johannes
Curators

Publications
1

Citation Title
Hitch et al., 2025, Nature Communications HiBC: a publicly available collection of bacterial strains isolated from the human gut
Effective publication



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