Suffridge, Christopher P.


Publications
1

Whole cell affinity for 4‐amino‐5‐hydroxymethyl‐2‐methylpyrimidine (<scp>HMP</scp>) in the marine bacterium Candidatus<scp>Pelagibacter</scp> st. <scp>HTCC7211</scp> explains marine dissolved <scp>HMP</scp> concentrations

Citation
Brennan et al. (2024). Environmental Microbiology Reports 16 (5)
Names
Ca. Pelagibacter
Abstract
AbstractVitamin B1 is a universally required coenzyme in carbon metabolism. However, most marine microorganisms lack the complete biosynthetic pathway for this compound and must acquire thiamin, or precursor molecules, from the dissolved pool. The most common version of Vitamin B1 auxotrophy is for thiamin's pyrimidine precursor moiety, 4‐amino‐5‐hydroxymethyl‐2‐methylpyrimidine (HMP). Frequent HMP auxotrophy in plankton and vanishingly low dissolved concentrations (approximately 0.1–50 pM) sugg