Human head and body lice host the obligate endosymbiotic bacterium “
Candidatus
Riesia pediculicola.” In this announcement, we describe the complete genome sequence of a “
Ca.
Riesia pediculicola” strain isolated from the human head louse,
Pediculus humanus
subsp.
capitis
. The inter- and intraspecific variations of endosymbiont genomes were investigated, and this strain was found to display high-level variations in its genome.