mSphere


Publications
4

Discovery of an Antarctic Ascidian-Associated Uncultivated Verrucomicrobia with Antimelanoma Palmerolide Biosynthetic Potential

Citation
Murray et al. (2021). mSphere 6 (6)
Names
“Synoicihabitans palmerolidicus”
Abstract
Palmerolide A has potential as a chemotherapeutic agent to target melanoma. We interrogated the microbiome of the Antarctic ascidian, Synoicum adareanum , using a cultivation-independent high-throughput sequencing and bioinformatic strategy.

Globally Abundant “ Candidatus Udaeobacter” Benefits from Release of Antibiotics in Soil and Potentially Performs Trace Gas Scavenging

Citation
Willms et al. (2020). mSphere 5 (4)
Names
Ca. Udaeobacter
Abstract
Soil bacteria have been investigated for more than a century, but one of the most dominant terrestrial groups on Earth, “ Candidatus Udaeobacter,” remains elusive and largely unexplored. Its natural habitat is considered a major reservoir of antibiotics, which directly or indirectly impact phylogenetically diverse microorganisms. Here, we found that “ Ca. Udaeobacter” representatives exhibit multidrug resistance and not only evade harm

Functional and Comparative Genomic Analysis of Integrated Prophage-Like Sequences in “ Candidatus Liberibacter asiaticus”

Citation
Dominguez-Mirazo et al. (2019). mSphere 4 (6)
Names
Ca. Liberibacter asiaticus
Abstract
Huanglongbing (HLB) disease is threatening citrus production worldwide. The causative agent is “ Candidatus Liberibacter asiaticus.” Prior work using mapping-based approaches identified prophage-like sequences in some “ Ca. Liberibacter asiaticus” genomes but not all. Here, we utilized a de novo approach that expands the number of prophage-like elements found in “ Ca. Liberibacter asiatic

A Small Wolbachia Protein Directly Represses Phage Lytic Cycle Genes in “ Candidatus Liberibacter asiaticus” within Psyllids

Citation
Jain et al. (2017). mSphere 2 (3)
Names
Ca. Liberibacter asiaticus
Abstract
Host acquisition of a new microbial species can readily perturb the dynamics of preexisting microbial associations. Molecular cross talk between microbial associates may be necessary for efficient resource allocation and enhanced survival. Classic examples involve quorum sensing (QS), which detects population densities and is both used and coopted to control expression of bacterial genes, including host adaptation factors. We report that a 56-amino-acid repressor protein made by the