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Preliminary landscape of Candidatus Saccharibacteria in the human microbiome

Naud et al. (2023). Frontiers in Cellular and Infection Microbiology 13
Ca. Saccharibacteria
IntroductionCandidate Phyla Radiation (CPR) and more specifically Candidatus Saccharibacteria (TM7) have now been established as ubiquitous members of the human oral microbiota. Additionally, CPR have been reported in the gastrointestinal and urogenital tracts. However, the exploration of new human niches has been limited to date.MethodsIn this study, we performed a prospective and retrospective screening of TM7 in human samples using standard PCR, real-time PCR, scanning electron microscopy (SE